Respiration of hydrogenosomes of Tritrichomonas foetus. II. Effect of CoA on pyruvate oxidation.

@article{Mueller1978RespirationOH,
  title={Respiration of hydrogenosomes of Tritrichomonas foetus. II. Effect of CoA on pyruvate oxidation.},
  author={Matthias Mueller and Donald G. Lindmark},
  journal={The Journal of biological chemistry},
  year={1978},
  volume={253 4},
  pages={1215-8}
}
Hydrogenosomes of the anaerobic flagellate Tritrichomonas foetus can use oxygen as terminal electron acceptor in pyruvate metabolism. In particles broken with the detergent, Triton X-100 or by repeated freezing and thawing, pyruvate-supported respiration is greatly enhanced by coenzyme A. Additions of small amounts of CoA result in a phenomenon resembling respiratory control. ADP and GDP also have a stimulatory effect; however, the rate of respiration in the presence of saturating… CONTINUE READING