Resorption is not essential for the stimulation of bone growth by hPTH-(1-34) in rats in vivo.

@article{Hock1989ResorptionIN,
  title={Resorption is not essential for the stimulation of bone growth by hPTH-(1-34) in rats in vivo.},
  author={Janet M. Hock and J R Hummert and Rogely Boyce and Jos{\'e} Segura Fonseca and Lawrence G. Raisz},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1989},
  volume={4 3},
  pages={449-58}
}
Chronic low doses of hPTH-(1-34) stimulate bone growth in rats in vivo. The objective of these studies was to determine if the anabolic effect of hPTH-(1-34) on rat bone in vivo is dependent on an initial stimulation of resorption by blocking resorption with either salmon calcitonin (CT) or dichloromethylene diphosphonate (Cl2MDP). Male Sprague-Dawley rats, 70-100 g, were treated with daily subcutaneous (SC) injections of vehicle (V) or hPTH-(1-34), 8 micrograms per 100 g (PTH), for 12 days. In… CONTINUE READING

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