Resonance Raman evidence for protein-induced out-of-plane distortion of the heme prosthetic group of mammalian lactoperoxidase.

Resonance Raman spectra have been acquired for resting state mammalian lactoperoxidase, LPO(N), and its six-coordinate, low-spin (6CLS) cyanide complex, LPO(CN), as well as for various heme l containing fragments resulting from partial or complete proteolytic digestion. These proteolytic fragments provide a useful set of reference compounds for analysis of… CONTINUE READING