Resolving controversies on the path to Alzheimer's therapeutics

  title={Resolving controversies on the path to Alzheimer's therapeutics},
  author={Dennis J Selkoe},
  journal={Nature Medicine},
Alzheimer's disease constitutes a personal and societal tragedy of immense proportions. Since 1960, research in laboratories and clinics worldwide has elucidated many features of this insidious and ultimately fatal syndrome, and this progress has led to initial human trials of potentially disease-modifying agents. However, some of these agents have already failed. Gnawing controversies and important gaps in our knowledge seem to cast additional doubt on the ability of the field to move forward… CONTINUE READING
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