Resolvin E1 analog RX-10045 0.1% reduces corneal stromal haze in rabbits when applied topically after PRK

@inproceedings{Torricelli2014ResolvinEA,
  title={Resolvin E1 analog RX-10045 0.1% reduces corneal stromal haze in rabbits when applied topically after PRK},
  author={Andr{\'e} Augusto Miranda Torricelli and Abirami Santhanam and Vandana Agrawal and Steven E Wilson},
  booktitle={Molecular vision},
  year={2014}
}
PURPOSE To perform a masked study to determine whether resolvin E1 (RvE1), a lipid-derived immunomodulator, could regulate the development of corneal haze and opacity-related myofibroblasts after opacity-generating high correction photorefractive keratectomy (PRK) in rabbits. METHODS Three groups of eight rabbits each were included in the study. Nine diopter (D) PRK for myopia was performed in each test cornea, and the eyes were treated with 30 µl of topical solution every 4 h (six times a… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Resolvin E1 improves tear production and decreases inflammation in a dry eye mouse model.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics • 2010
View 2 Excerpts

Resolvins and protectins: natural pharmacophores for resolution biology.

Prostaglandins, leukotrienes, and essential fatty acids • 2010
View 2 Excerpts