Resolution of Multimeric Forms of Circular Plasmids and Chromosomes.

@article{Crozat2014ResolutionOM,
  title={Resolution of Multimeric Forms of Circular Plasmids and Chromosomes.},
  author={Estelle Crozat and Florian Fournès and François Henri Cornet and Bernard Hallet and Philippe Louis Rousseau},
  journal={Microbiology spectrum},
  year={2014},
  volume={2 5}
}
One of the disadvantages of circular plasmids and chromosomes is their high sensitivity to rearrangements caused by homologous recombination. Odd numbers of crossing-over occurring during or after replication of a circular replicon result in the formation of a dimeric molecule in which the two copies of the replicon are fused. If they are not converted back to monomers, the dimers of replicons may fail to correctly segregate at the time of cell division. Resolution of multimeric forms of… CONTINUE READING

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