Resolution of Lung Inflammation by CD44

@article{Teder2002ResolutionOL,
  title={Resolution of Lung Inflammation by CD44},
  author={Priit Teder and R. William Vandivier and Dianhua Jiang and Jiurong Liang and Lauren Cohn and Ellen Pur{\'e} and Peter M Henson and Paul W. Noble},
  journal={Science},
  year={2002},
  volume={296},
  pages={155 - 158}
}
Successful repair after tissue injury and inflammation requires resolution of the inflammatory response and removal of extracellular matrix breakdown products. We have examined whether the cell-surface adhesion molecule and hyaluronan receptor CD44 plays a role in resolving lung inflammation. CD44-deficient mice succumb to unremitting inflammation following noninfectious lung injury, characterized by impaired clearance of apoptotic neutrophils, persistent accumulation of hyaluronan fragments at… 

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