Resolution of Lung Inflammation by CD44

@article{Teder2002ResolutionOL,
  title={Resolution of Lung Inflammation by CD44},
  author={P. Teder and R. Vandivier and D. Jiang and Jiurong Liang and L. Cohn and E. Pur{\'e} and P. Henson and P. Noble},
  journal={Science},
  year={2002},
  volume={296},
  pages={155 - 158}
}
Successful repair after tissue injury and inflammation requires resolution of the inflammatory response and removal of extracellular matrix breakdown products. We have examined whether the cell-surface adhesion molecule and hyaluronan receptor CD44 plays a role in resolving lung inflammation. CD44-deficient mice succumb to unremitting inflammation following noninfectious lung injury, characterized by impaired clearance of apoptotic neutrophils, persistent accumulation of hyaluronan fragments at… Expand
Matrix regulation of lung injury, inflammation, and repair: the role of innate immunity.
  • P. Noble, D. Jiang
  • Biology, Medicine
  • Proceedings of the American Thoracic Society
  • 2006
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