Resizing the genomic regulation of restenosis.

  title={Resizing the genomic regulation of restenosis.},
  author={Takumi Matsumoto and Paul M. Hwang},
  journal={Circulation research},
  volume={100 11},
With the introduction of drug eluting stents (DES) for percutaneous coronary interventions, restenosis appeared to be a problem of the past. However, the biology of arterial injury has returned to the limelight of clinical cardiology because of increased late-stent thrombosis associated with DES.1 As DES use initially increased, concerns were raised about altering the normal responses to arterial injury with antiproliferative drugs based on animal and human data.2 Since 2006, this concern has… CONTINUE READING