Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation

@inproceedings{Deshmukh2015ResistinAI,
  title={Resistin and interleukin-6 exhibit racially-disparate expression in breast cancer patients, display molecular association and promote growth and aggressiveness of tumor cells through STAT3 activation},
  author={Sachin Kumar Deshmukh and Sanjeev Kumar Srivastava and Arun Bhardwaj and Ajay Singh and Nikhil Tyagi and Saravanakumar Marimuthu and Donna Lynn Dyess and Valeria Dal Zotto and James Elliot Carter and Seema Singh},
  booktitle={Oncotarget},
  year={2015}
}
African-American (AA) women with breast cancer (BC) are diagnosed with more aggressive disease, have higher risk of recurrence and poorer prognosis as compared to Caucasian American (CA) women. Therefore, it is imperative to define the factors associated with such disparities to reduce the unequal burden of cancer. Emerging data suggest that inherent differences exist in the tumor microenvironment of AA and CA BC patients, however, its molecular bases and functional impact have remained poorly… CONTINUE READING