Resistin -420C>G promoter variant and colorectal cancer risk.

  title={Resistin -420C>G promoter variant and colorectal cancer risk.},
  author={Touraj Mahmoudi and Khatoon Karimi and Maral Arkani and Hamid Farahani and Mohsen Vahedi and Reza Dabiri and Hossein Nobakht and Asadollah Asadi and Mojgan Mirakhorli and Benafsheh Arshi and Arash Derakhshan and Mohammad Reza Zali},
  journal={The International journal of biological markers},
  volume={29 3},
PURPOSES Obesity is associated with an increased risk of colorectal cancer (CRC), and ghrelin (GHRL) and resistin (RETN) are thought to be related to obesity. Our aim was to investigate whether GHRL and RETN gene variants are associated with CRC risk. MATERIALS AND METHODS All 414 subjects, including 197 cases with CRC and 217 controls, were genotyped for the GHRL (rs26802) and RETN (rs1862513) or -420 C>G gene variants using the PCR-RFLP method. RESULTS Our findings indicated that the RETN… CONTINUE READING

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