Resistance training reduces the acute exercise-induced increase in muscle protein turnover.

@article{Phillips1999ResistanceTR,
  title={Resistance training reduces the acute exercise-induced increase in muscle protein turnover.},
  author={Stuart M Phillips and K. Tipton and A. Ferrando and R. Wolfe},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={1999},
  volume={276 1},
  pages={E118-E124}
}
We examined the effect of resistance training on the response of mixed muscle protein fractional synthesis (FSR) and breakdown rates (FBR) by use of primed constant infusions of [2H5]phenylalanine and [15N]phenylalanine, respectively, to an isolated bout of pleiometric resistance exercise. Trained subjects, who were performing regular resistance exercise (trained, T; n = 6), were compared with sedentary, untrained controls (untrained, UT; n = 6). The exercise test consisted of 10 sets (8… Expand
Resistance-training-induced adaptations in skeletal muscle protein turnover in the fed state.
TLDR
It is demonstrated that resistance training resulted in an elevated resting muscleprotein turnover but an attenuation of the acute response of muscle protein turnover to a single bout of resistance exercise, which attenuated the acute exercise-induced rise in FSR. Expand
Resistance training alters the response of fed state mixed muscle protein synthesis in young men.
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It is concluded that resistance training attenuates the protein synthetic response to acute resistance exercise, despite higher initial increases in FSR, by shortening the duration for which protein synthesis is elevated. Expand
Fasted‐state skeletal muscle protein synthesis after resistance exercise is altered with training
TLDR
Resistance training modified the acute response of MPS to resistance exercise by dampening the increased synthesis of non‐myofibrillar proteins while maintaining the synthesis of myofibrillsar proteins. Expand
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TLDR
High-intensity RE without prior training impacts integrative mixed muscle and myofibrillar 24-hour FSR, perhaps without altering total responses. Expand
Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men.
TLDR
It is concluded that a small dose of whey protein with carbohydrate (21 g) can stimulate a rise in MPS after resistance exercise in trained young men that would be supportive of a positive net protein balance, which, over time, would lead to hypertrophy. Expand
Aerobic exercise training increases skeletal muscle protein turnover in healthy adults at rest.
TLDR
It is shown that aerobic training for 4 wk increases skeletal muscle protein turnover in previously unfit subjects, and Endurance training improved cardiovascular fitness, with a significant increase in VO(2 peak) and a significant decrease in running time on a standard course. Expand
Resistance Exercise–induced Regulation of Muscle Protein Synthesis to Intraset Rest
TLDR
The results show that CLU is a viable anabolic option by preserving power output with similar MPS stimulation when compared with the TRD condition in trained young adults. Expand
Short-term training: when do repeated bouts of resistance exercise become training?
  • Stuart M Phillips
  • Medicine
  • Canadian journal of applied physiology = Revue canadienne de physiologie appliquee
  • 2000
TLDR
Proposed training-induced changes in neural drive are hypothesized to increase strength due to increased synchrony of motor unit firing, reducedant agonist muscle activity, and/or a reduction in any bilateral strength deficit. Expand
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TLDR
A minor advantage of protein supplementation over carbohydrate supplementation during resistance training on mechanical muscle function was found, and the present results may have relevance for individuals who are particularly interested in gaining muscle size. Expand
Concurrent exercise and muscle protein synthesis: implications for exercise countermeasures in space.
TLDR
It appears the anabolic response to resistance exercise cannot explain the attenuated muscle mass and strength gains imposed by chronic concurrent aerobic and resistance training, nor the response of space crews to in-flight concurrent countermeasures. Expand
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