Resistance to trimethoprim-sulfamethoxazole.

@article{Huovinen2001ResistanceTT,
  title={Resistance to trimethoprim-sulfamethoxazole.},
  author={Pentti Huovinen},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2001},
  volume={32 11},
  pages={1608-14}
}
  • Pentti Huovinen
  • Published 2001 in
    Clinical infectious diseases : an official…
Sulfonamides have a glorious history. In 1935, they were the first class of true antimicrobial agents with life-saving potency. Today, 66 years later, increased bacterial resistance to sulfonamides and to trimethoprim (TMP), a synthetic antimicrobial agent that is 30 years younger than sulfonamides, has limited their use to only a few indications. In the treatment and prophylaxis of patients with urinary tract infections, trimethoprim-sulfamethoxazole (TMP-SMZ) or TMP alone is still considered… CONTINUE READING

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