Resistance to the antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian postmenopausal women.

@article{Fried2010ResistanceTT,
  title={Resistance to the antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian postmenopausal women.},
  author={Susan K. Fried and Thomas J Tittelbach and Jacob Blumenthal and Urmila T Sreenivasan and Linda Robey and Jamie Yi and Sumbul Khan and Courtney A Hollender and Alice S Ryan and Andrew P. Goldberg},
  journal={Journal of lipid research},
  year={2010},
  volume={51 5},
  pages={
          1193-200
        }
}
High fatty acid (FA) flux is associated with systemic insulin resistance, and African-American (AA) women tend to be more insulin resistant. We assessed possible depot and race difference in the antilipolytic effect of insulin in adipocytes isolated from abdominal (Abd) and gluteal (Glt) subcutaneous (sc) adipose tissue of overweight, postmenopausal AA and Caucasian (C) women. Percent body fat, fasting insulin, visceral adiposity, and adipocyte size was higher in AA women. Disinhibited… CONTINUE READING

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