Resistance to polymyxins in Gram-negative organisms.

  title={Resistance to polymyxins in Gram-negative organisms.},
  author={Katy Jeannot and Arnaud Bolard and Patrick Pl{\'e}siat},
  journal={International journal of antimicrobial agents},
  volume={49 5},
Polymyxins have recently been re-introduced into the therapeutic arsenal to combat infections caused by multidrug-resistant Gram-negative bacteria. However, the emergence of strains resistant to these last-resort drugs is becoming a critical issue in a growing number of countries. Both intrinsic and transferable mechanisms of polymyxin resistance have been… CONTINUE READING