Resistance to l-methionine-S-sulfoximine in Chlamydomonas reinhardtii is due to an alteration in a general amino acid transport system

Abstract

It was suggested that the mutant ARF1 of Chlamydomonas reinhardtii is resistant to l-methionine-S-sulfoximine (MSX, an irreversible inhibitor of glutamine synthetase, EC 6.3.1.2) because this strain degraded and utilized this compound as a nitrogen source for growth (A.R. Franco et al., 1996, Plant Physiol 110: 1215–1222). Resistance to MSX has now been… (More)
DOI: 10.1007/s004250050451

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