Resistance to enediyne antitumor antibiotics by CalC self-sacrifice.

Abstract

Antibiotic self-resistance mechanisms, which include drug elimination, drug modification, target modification, and drug sequestration, contribute substantially to the growing problem of antibiotic resistance among pathogenic bacteria. Enediynes are among the most potent naturally occurring antibiotics, yet the mechanism of resistance to these toxins has… (More)

Topics

  • Presentations referencing similar topics