Resistance to blockade by saralasin of effect of ACE inhibitors in conscious sodium-restricted dog.


Comparison of the effect of captopril and enalaprilat was made on mean systemic arterial blood pressure (BP), renal blood flow (RBF), and renal vascular resistance (RVR) of conscious sodium-replete and sodium-restricted dogs (plasma renin activity = 6.66 ng angiotensin BP was decreased by -8 +/- 2 mmHg and RBF was increased by 34 +/- 12 ml/min… (More)


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