Resistance to Systemic Inflammation and Multi Organ Damage after Global Ischemia/Reperfusion in the Arctic Ground Squirrel

@inproceedings{Bogren2014ResistanceTS,
  title={Resistance to Systemic Inflammation and Multi Organ Damage after Global Ischemia/Reperfusion in the Arctic Ground Squirrel},
  author={Lori K. Bogren and Jasmine M. Olson and JoAnna Carpluk and Jeanette M. Moore and Kelly L Drew},
  booktitle={PloS one},
  year={2014}
}
INTRODUCTION Cardiac arrest (CA) and hemorrhagic shock (HS) are two clinically relevant situations where the body undergoes global ischemia as blood pressure drops below the threshold necessary for adequate organ perfusion. Resistance to ischemia/reperfusion (I/R) injury is a characteristic of hibernating mammals. The present study sought to determine if arctic ground squirrels (AGS) are protected from systemic inflammation and multi organ damage after CA- or HS-induced global I/R and if, for… CONTINUE READING
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