Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya.

  title={Resistance to HIV-1 infection among persistently seronegative prostitutes in Nairobi, Kenya.},
  author={Keith R Fowke and Nico J. D. Nagelkerke and Joshua Kimani and J. Neil Simonsen and Aggrey Omu Anzala and Job Joab Bwayo and Kelly S Macdonald and Elizabeth N. Ngugi and Francis Allan Plummer},
  volume={348 9038},
BACKGROUND There is indirect evidence that HIV-1 exposure does not inevitably lead to persistent infection. Heterogeneity in susceptibility to infection could be due to protective immunity. The objective of this study was to find out whether in highly HIV-1-exposed populations some individuals are resistant to infection. METHODS We did an observational cohort study of incident HIV-1 infection-among 424 initially HIV-1-seronegative prostitutes in Nairobi, Kenya, between 1985 and 1994. 239… CONTINUE READING
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