Resistance to Antimalarial Drugs: Molecular, Pharmacologic, and Clinical Considerations

Abstract

One of the greatest obstacles to the control of malaria has been the spread of resistance to drugs used on a large scale. This review provides an update of the current understanding of the molecular basis for antimalarial drug resistance. Parasite intrinsic resistance is just one component that determines the in vivo efficacy of a drug. Human immune… (More)
DOI: 10.1203/PDR.0b013e3181a0977e

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