Resistance to Alzheimer's pathology is associated with nuclear hypertrophy in neurons.

@article{Riudavets2007ResistanceTA,
  title={Resistance to Alzheimer's pathology is associated with nuclear hypertrophy in neurons.},
  author={Miguel Angel Riudavets and Diego Iacono and Susan M. Resnick and Richard J. O'Brien and Alan B. Zonderman and Lee J. Martin and Gay L Rudow and Olga Pletnikova and Juan C Troncoso},
  journal={Neurobiology of aging},
  year={2007},
  volume={28 10},
  pages={1484-92}
}
This study focuses on the morphometric changes of neurons in asymptomatic Alzheimer's disease (AD), a state characterized by the presence of AD lesions in subjects without cognitive impairment. In autopsy brains, we used stereological methods to compare the cell body and nuclear volumes of anterior cingulate gyrus (ACG) and CA1 hippocampal neurons in… CONTINUE READING