Resistance of neisseria meningitidis to the toxic effects of heme iron and other hydrophobic agents requires expression of ght.


Several genetic systems that allow the use of iron-protoporphyrin IX (heme) have been described for the pathogenic bacterium Neisseria meningitidis. However, many questions about the process of heme acquisition and utilization remain to be answered. To isolate and analyze unidentified genes that play a role in heme iron uptake and utilization, a Himar1… (More)


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