Resistance of influenza A virus to amantadine and rimantadine: results of one decade of surveillance.

@article{Belshe1989ResistanceOI,
  title={Resistance of influenza A virus to amantadine and rimantadine: results of one decade of surveillance.},
  author={Robert B. Belshe and By Steve Burk and Frances Newman and R L Cerruti and I S Sim},
  journal={The Journal of infectious diseases},
  year={1989},
  volume={159 3},
  pages={430-5}
}
All clinical isolates of influenza A viruses from patients in Huntington, West Virginia, during the decade 1978-1988 were tested, and 65 of 65 H1N1 and 176 of 181 H3N2 viruses were susceptible to the antiviral action of amantadine and rimantadine. The five resistant viruses were obtained from three members of a family undergoing therapy or prophylaxis with… CONTINUE READING