Resistance of Staphylococcus aureus to the Action of Penicillin.∗

@article{Rammelkamp1942ResistanceOS,
  title={Resistance of Staphylococcus aureus to the Action of Penicillin.∗},
  author={Charles Henry Rammelkamp and Thelma Maxon},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  year={1942},
  volume={51},
  pages={386 - 389}
}
Conclusion Strains of Staphylococcus aureus vary only slightly in their susceptibility to the antibacterial action of penicillin. By growing the organism in increasing concentrations of penicillin over a long period it was possible to render the organism resistant to penicillin. Similar degrees of increased resistance were found in 4 strains of staphylococci isolated during the course of penicillin therapy for localized infections. 

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