Resistance of Helicobacter pylori to antibiotics.

  title={Resistance of Helicobacter pylori to antibiotics.},
  author={Francis M{\'e}graud},
  journal={Alimentary pharmacology & therapeutics},
  volume={11 Suppl 1},
Resistance of Helicobacter pylori to antibiotics included in current regimens used to eradicate H. pylori is a major reason for failure. The definition of resistance is not simple, and the clinical relevance of in vitro results must be considered. The different methods of testing antibiotics cannot apply in all cases. Resistance to clarithromycin has a low prevalence rate (< 10%) and its mechanism is well defined (point mutation on the 23S rRNA genes, and decreased binding of the antibiotics to… CONTINUE READING


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