Resistance of Bovine Spongiform Encephalopathy (BSE) Prions to Inactivation

@article{Giles2008ResistanceOB,
  title={Resistance of Bovine Spongiform Encephalopathy (BSE) Prions to Inactivation},
  author={Kurt Giles and David V. Glidden and Robyn Beckwith and Rose Seoanes and David J Peretz and Stephen J. DeArmond and Stanley B Prusiner},
  journal={PLoS Pathogens},
  year={2008},
  volume={4},
  pages={107 - 117}
}
Distinct prion strains often exhibit different incubation periods and patterns of neuropathological lesions. Strain characteristics are generally retained upon intraspecies transmission, but may change on transmission to another species. We investigated the inactivation of two related prions strains: BSE prions from cattle and mouse-passaged BSE prions, termed 301V. Inactivation was manipulated by exposure to sodium dodecyl sulfate (SDS), variations in pH, and different temperatures… CONTINUE READING
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References

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Regression models and life-tables

  • DR Cox
  • J R Stat Soc Ser A Method
  • 1972
Highly Influential
8 Excerpts

Disinfection of prions

  • K Giles, S Supattapone, D Peretz, DV Glidden, H Baron
  • 2007

Disinfection of prions. In: Zhu PC, ed. New Biocides Development: The Combined Approach of Chemistry and Microbiology

  • K Giles, S Supattapone, D Peretz, DV Glidden, H Baron
  • 2007
1 Excerpt

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