The selection of heavy metal resistance by microorganisms often promotes for antibiotic resistance in the environment. This work investigates the potentials of selected microorganisms isolated from dumpsite leachate from Awotan dumpsite at Ibadan in Ibadan south, Oyo State to tolerate some heavy metals such as lead (Pb), Nickel (Ni), Copper (Cu) and Arsenic (As) found in the leachate and also determine their antibiotic resistance pattern. Twenty six (26) bacterial isolates belonging to seven genera were obtained from the samples of leachate. The identification of the bacteria isolated revealed they belongs to Escherichia coli, Pseudomonas sp, Proteus sp, Bacillus spp, Arthrobacter sp, Klebsiella pneumonia, Enterobacter cloacae and Staphylococcus sp. Tolerance ability of the microbial isolates to heavy metals was determined by cultivating the isolates in a basal medium in which different concentrations of heavy metals compound ranging from 1mM to 3mM was incorporated. Some of the organisms had high MIC values for Pb+ and Cu++ and low MIC value for Ni+ and Ar2+. The MIC result shows low toxicity and high toxicity respectively of the heavy metals to the organisms. On the other hand, the isolates also exhibited high tolerance to most of the antibiotics like Ampiclox (100%), Gentamicin (100%), Ciprofloxacin (50.0%), Septrin (75%), and Streptomycin (75%). The resistance of these organisms to both metals and antibiotics could cause hazard into the environment and present very serious health implication because of the ability of these organisms to pass these resistant genes which may be transfer together via plasmids to other microbial cell around will affect a whole bacterial population thereby complicating treatment.