Resistance mutations before and after tenofovir regimen failure in HIV-1 infected patients.

@article{Wirden2005ResistanceMB,
  title={Resistance mutations before and after tenofovir regimen failure in HIV-1 infected patients.},
  author={Marc Wirden and Anne Genevi{\`e}ve Marcelin and Anne Simon and Myriam Kirstetter and Roland Tubiana and M A Valantin and Luc Paris and Manuela Bonmarchand and Françoise Conan and Laurence Kalkias and Christine Katlama and Vincent Calvez},
  journal={Journal of medical virology},
  year={2005},
  volume={76 3},
  pages={297-301}
}
So far, no study has examined the real impact of tenofovir (TDF)-regimen failure taking into account all patients in a current clinical practice. The aim of this study was to compare the nucleoside reverse transcriptase inhibitors (NRTIs) mutation profiles observed before TDF initiation and after TDF-regimen failure. All patients with genotypic resistance tests performed in this context were selected from the database of the department of virology. The patients were categorized in two groups… CONTINUE READING