Resistance and viral subtypes: how important are the differences and why do they occur?

  title={Resistance and viral subtypes: how important are the differences and why do they occur?},
  author={Bluma G Brenner},
  journal={Current opinion in HIV and AIDS},
  volume={2 2},
PURPOSE OF REVIEW The global HIV-1 pandemic has evolved to include 11 subtypes and 34 circulating recombinant forms. Our knowledge of HIV-1 response to antiretroviral drugs and emergent drug resistance has, however, been limited to subtype B infections circulating in Europe and North America, with little comparative information on non-B subtypes representing approximately 90% of worldwide epidemics. This review summarizes publications in the past year that highlight intersubtype differences… CONTINUE READING


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