Resiniferatoxin for treatment of lifelong premature ejaculation: A preliminary study

@article{Shi2014ResiniferatoxinFT,
  title={Resiniferatoxin for treatment of lifelong premature ejaculation: A preliminary study},
  author={Bentao Shi and Xue-Yi Li and Jing Chen and Boxing Su and Xianxin Li and Shangqi Yang and Zhichen Guan and Run-han Wang},
  journal={International Journal of Urology},
  year={2014},
  volume={21}
}
To evaluate the efficacy of resiniferatoxin in the treatment of patients with lifelong premature ejaculation. 

Response to Re: Resiniferatoxin for treatment of lifelong premature ejaculation: A preliminary study

  • B. Shi
  • Medicine
    International journal of urology : official journal of the Japanese Urological Association
  • 2017
1 Porst H, Montorsi F, Rosen RC, Gaynor L, Grupe S, Alexander J. The premature ejaculation prevalence and attitudes (PEPA) survey: prevalence, comorbidities and professional help-seeking. Eur. Urol.

Response to Editorial Comment from Dr Sato to Resiniferatoxin for treatment of lifelong premature ejaculation: A preliminary study

  • B. Shi
  • Medicine
    International journal of urology : official journal of the Japanese Urological Association
  • 2014
TLDR
It is suggested that the soaking solution should be further tested evaluating not only the “timing” (intravaginal ejaculation latency time), but also the patients’ and partners’ satisfaction levels in order to better determine if RTX is a viable treatment for premature ejaculation.

Editorial Comment from Dr Sato to Resiniferatoxin for treatment of lifelong premature ejaculation: A preliminary study

  • Yoshikazu Sato
  • Medicine
    International journal of urology : official journal of the Japanese Urological Association
  • 2014
TLDR
This is the first study, to the authors' knowledge, that shows a potentially effective method using RTX for PE treatment, particularly, for patients with redundant prepuce, and the safety of this concentration is obvious.

Editorial Comment from Dr Mirone et al. to Resiniferatoxin for treatment of lifelong premature ejaculation: A preliminary study

TLDR
If the effect of a single application of RTX for PE is maintained for a few months or more, the same as the effect for overactive bladder and interstitial cystitis, RTX could have an important clinical position as a treatment option for PE.

Current and emerging therapies in premature ejaculation: Where we are coming from, where we are going

TLDR
The goal of the present article was to review the commonly used treatment regimens used in the treatment of premature ejaculation, as well as to introduce and discuss the newest treatment routines under study for the Treatment of Premature ejaculation.

Re: Resiniferatoxin for treatment of lifelong premature ejaculation: A preliminary study

  • Yong ZhuQ. Zeng
  • Medicine
    International journal of urology : official journal of the Japanese Urological Association
  • 2017
TLDR
As secondary urothelial tumors are one of the rarest “recurrences” after radical cystectomy, it is concur with Besiroglu that the early detection of these recurrences should be prioritized.

Progresses in pharmaceutical and surgical management of premature ejaculation

TLDR
The pharmaceutical therapy that is currently being used in clinical practice for the management of PE is still the main choice globally due to its good efficacy and surgery may be a choice for patients who are resistant to medication.

References

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[Intravesical instillation of resiniferatoxin for the patients with interstitial cystitis].

TLDR
Though RTX treatment requires general anesthesia against severe bladder pain it is effective for selected patients with interstitial cystitis and can be potentially used as one of the treatment options.

Vanilloid (Capsaicin) receptors and mechanisms.

TLDR
This paper focuses on hot pepper, which is eaten on a daily basis by an estimated one-quarter of the world’s population and has potential to be a biological target for regenerative medicine.

Current therapeutic strategies for premature ejaculation and future perspectives.

TLDR
This review focuses on the current therapeutic strategies and future treatment perspectives for PE and describes some novel oral agents and some newer methods of drug administration that provide important relief to PE patients.

Intravesical instillation of resiniferatoxin for the treatment of overactive bladder

TLDR
Intravesical instillation of RTX is efficacious treatment without side effects and can be a promising therapeutic method for patients with overactive bladder.

A preliminary study on intravesical capsaicin for the treatment of obstinate urethral syndrome

TLDR
Intravesical capsaicin could be a long lasting effective therapeutic method for patients with obstinate urethral syndrome.

Sexual function of premature ejaculation patients assayed with Chinese Index of Premature Ejaculation.

TLDR
The CIPE-5 is a useful method for the evaluation of sexual function of patients with PE and can be used as a clinical endpoint for clinical trials studying the efficacy of pharmacological intervention.

Premature ejaculation: definition and prevalence

  • C. CarsonK. Gunn
  • Medicine, Psychology
    International Journal of Impotence Research
  • 2006
TLDR
An improved and universal definition and understanding of PE and its epidemiology will improve the clinical management ofPE and the success of future epidemiologic studies and clinical trials.

The role of short frenulum and the effects of frenulectomy on premature ejaculation.

TLDR
Short frenulum is a genital anomaly found in 43% of individuals affected by lifelong PE in the data set and the role of frenulectomy as first-line treatment for this condition is investigated.