Residue ionization and ion transport through OmpF channels.

  title={Residue ionization and ion transport through OmpF channels.},
  author={Ekaterina M. Nestorovich and Tatiana K. Rostovtseva and Sergey M. Bezrukov},
  journal={Biophysical journal},
  volume={85 6},
Single trimeric channels of the general bacterial porin, OmpF, were reconstituted into planar lipid membranes and their conductance, selectivity, and open-channel noise were studied over a wide range of proton concentrations. From pH 1 to pH 12, channel transport properties displayed three characteristic regimes. First, in acidic solutions, channel conductance is a strong function of pH; it increases by approximately threefold as the proton concentration decreases from pH 1 to pH 5. This rise… CONTINUE READING


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Structural and functional alterations of a colicin - resistant mutant of OmpF porin from E . coli

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