Residue Modification and Mass Spectrometry for the Investigation of Structural and Metalation Properties of Metallothionein and Cysteine-Rich Proteins

Abstract

Structural information regarding metallothioneins (MTs) has been hard to come by due to its highly dynamic nature in the absence of metal-thiolate cluster formation and crystallization difficulties. Thus, typical spectroscopic methods for structural determination are limited in their usefulness when applied to MTs. Mass spectrometric methods have… (More)
DOI: 10.3390/ijms18050913

Topics

8 Figures and Tables

Cite this paper

@inproceedings{Irvine2017ResidueMA, title={Residue Modification and Mass Spectrometry for the Investigation of Structural and Metalation Properties of Metallothionein and Cysteine-Rich Proteins}, author={Gordon W Irvine and Martin J. Stillman}, booktitle={International journal of molecular sciences}, year={2017} }