Residual effects and skills related to driving after a single oral administration of diazepam, medazepam or lorazepam.

@article{Seppl1976ResidualEA,
  title={Residual effects and skills related to driving after a single oral administration of diazepam, medazepam or lorazepam.},
  author={Kari Sepp{\"a}l{\"a} and Kari Korttila and S H{\"a}kkinen and Markku Linnoila},
  journal={British journal of clinical pharmacology},
  year={1976},
  volume={3 5},
  pages={831-41}
}
Psychomotor skills and visual functions related to driving were measured double-blind cross-over in ten healthy volunteers before, and 1,3,5 and 7 h after a single oral administration of diazepam (10mg), medazepam (15 mg) or lorazepam (2.5 mg). The late effects of lorazepam were tested in seven other subjects 12 and 24 h after the administration. Lorazepam impaired almost all the measured skills more (P less than 0.05 to 0.001) than diazepam, medizepam or the placebo. The lorazepam impairment… CONTINUE READING

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