Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy.

@article{Pomerantz2001ResidualHR,
  title={Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy.},
  author={Roger J. Pomerantz},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2001},
  volume={55 1},
  pages={
          7-15
        }
}
Residual HIV-1 disease remains in the vast majority of patients treated with even the most intensive highly active antiretroviral therapy (HAART). There are at least two well-described molecular mechanisms for HIV-1 persistence in these patients. These include proviral latency in resting CD4+ T-cells, as well as 'cryptic' residual viral replication. As well, potential sanctuary sites, including the brain and testes, may be important areas which will hinder HIV-1 eradication attempts. It is not… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 210 CITATIONS, ESTIMATED 63% COVERAGE

Measuring the latent reservoir in vivo.

  • The Journal of clinical investigation
  • 2016
VIEW 14 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliter.

  • Journal of virological methods
  • 2011
VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Targeting the Brain Reservoirs: Toward an HIV Cure

  • Front. Immunol.
  • 2016
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

On HIV-1 latency and viral reservoirs

VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

ASPECTS ON LATENCY IN HIV-1 INFECTION

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1991
2019

CITATION STATISTICS

  • 10 Highly Influenced Citations

  • Averaged 7 Citations per year from 2017 through 2019