Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data

@inproceedings{Imoto2004ResidualBA,
  title={Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data},
  author={Seiya Imoto and Tomoyuki Higuchi and SunYong Kim and Euna Jeong and Satoru Miyano},
  booktitle={CMSB},
  year={2004}
}
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outliers that interrupt the estimation of accurate gene networks. In addition, some relationships between genes are nonlinear, and linear models thus are not enough for capturing such… CONTINUE READING