Resident microbiota affect Bordetella pertussis infectious dose and host specificity.

  title={Resident microbiota affect Bordetella pertussis infectious dose and host specificity.},
  author={Laura S. Weyrich and Heather A. Feaga and J. Park and Sarah J. Muse and Chetan Y Safi and O. Rolin and S. Young and E. Harvill},
  journal={The Journal of infectious diseases},
  volume={209 6},
  • Laura S. Weyrich, Heather A. Feaga, +5 authors E. Harvill
  • Published 2014
  • Biology, Medicine
  • The Journal of infectious diseases
  • Before contacting host tissues, invading pathogens directly or indirectly interact with host microbiota, but the effects of such interactions on the initial stages of infection are poorly understood. Bordetella pertussis is highly infectious among humans but requires large doses to colonize rodents, unlike a closely related zoonotic pathogen, Bordetella bronchiseptica, raising important questions about the contributions of bacterial competition to initial colonization and host selection. We… CONTINUE READING
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