Residence time modeling of hot melt extrusion processes.

  title={Residence time modeling of hot melt extrusion processes.},
  author={Elena Reitz and Helmut Podhaisky and David R. Ely and Markus Thommes},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  volume={85 3 Pt B},
The hot melt extrusion process is a widespread technique to mix viscous melts. The residence time of material in the process frequently determines the product properties. An experimental setup and a corresponding mathematical model were developed to evaluate residence time and residence time distribution in twin screw extrusion processes. The extrusion process was modeled as the convolution of a mass transport process described by a Gaussian probability function, and a mixing process… CONTINUE READING

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