Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene.

@article{Chen2012ReshapingOG,
  title={Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene.},
  author={Sidi Chen and Xiaochun Ni and Benjamin H. Krinsky and Yong E. Zhang and Maria D. Vibranovski and Kevin P. White and Manyuan Long},
  journal={The EMBO journal},
  year={2012},
  volume={31 12},
  pages={2798-809}
}
New genes originate frequently across diverse taxa. Given that genetic networks are typically comprised of robust, co-evolved interactions, the emergence of new genes raises an intriguing question: how do new genes interact with pre-existing genes? Here, we show that a recently originated gene rapidly evolved new gene networks and impacted sex-biased gene expression in Drosophila. This 4-6 million-year-old factor, named Zeus for its role in male fecundity, originated through retroposition of a… CONTINUE READING