Reservoirs of HIV replication after successful combined antiretroviral treatment.

@article{Belmonte2003ReservoirsOH,
  title={Reservoirs of HIV replication after successful combined antiretroviral treatment.},
  author={Liliana Belmonte and Patricia Bar{\'e} and Mar{\'i}a Marta de E de Bracco and Beatriz H Ruibal-Ares},
  journal={Current medicinal chemistry},
  year={2003},
  volume={10 4},
  pages={
          303-12
        }
}
Sustained reduction of viral replication can be achieved in HIV infected patients after treatment with combinations of drugs (HAART) that inhibit the viral reverse transcriptase, and protease enzymes. However, replication competent virus can still be recovered from latently infected resting memory CD4+ T-cell lymphocytes. Moreover, "covert" virus replication has been demonstrated in patients who experienced reductions in plasma viremia to levels below the limit of detection of the most… CONTINUE READING