Reservoir of four organisms associated with bacterial vaginosis suggests lack of sexual transmission

  title={Reservoir of four organisms associated with bacterial vaginosis suggests lack of sexual transmission},
  author={Elisabeth Holst},
  journal={Journal of Clinical Microbiology},
  pages={2035 - 2039}
  • E. Holst
  • Published 1 September 1990
  • Medicine, Biology
  • Journal of Clinical Microbiology
This study consisted of a search for the possible reservoir and mode of spread of the four bacterial vaginosis-associated organisms Mobiluncus mulieris, Mobiluncus curtisii, Mycoplasma hominis, and Gardnerella vaginalis. Their occurrence in rectal, oral, and pharyngeal specimens from women with and without bacterial vaginosis, their male sexual consorts, four homosexual men, and children (altogether, 374 people) was studied. Genital samples were also obtained from all adults. All four organisms… 

Bacterial vaginosis

  • C. Spiegel
  • Medicine, Biology
    Clinical Microbiology Reviews
  • 1991
The mechanisms by which the BV-associated flora causes the signs of BV are not well understood, but a role for H2O2-producing Lactobacillus spp.

Evolving issues in understanding and treating bacterial vaginosis

  • J. Marrazzo
  • Medicine, Biology
    Expert review of anti-infective therapy
  • 2004
Bacterial vaginosis has been consistently associated with numerous adverse sequelae related to the upper genital tract, including pelvic inflammatory disease and postsurgical infection in the setting of invasive gynecologic procedures, and may increase women’s risk of acquiring HIV infection.

Gardnerella vaginalis isolated from patients with bacterial vaginosis and from patients with healthy vaginal ecosystems.

G. vaginalis isolates from patients with bacterial vaginosis and from patients without BV were examined, and biotype 5 was predominantly associated with a healthy vaginal ecosystem and biotypes 5 and 7 were the most resistant to metronidazole.

Gardnerella vaginalis: characteristics, clinical considerations, and controversies

  • B. Catlin
  • Biology, Medicine
    Clinical Microbiology Reviews
  • 1992
Controversy over the etiology of bacterial vaginosis was largely resolved by studies using improved media and methods for the isolation and identification of bacteria in vaginal fluids and standardization of criteria for clinical and laboratory diagnosis.

Treatment and Management of Bacterial Vaginosis in Pregnancy: Current and Future Perspectives

Black race, higher-risk sexual activity, frequent vaginal douching and the substantial reduction of hydrogen peroxide-producing Lactobacillus spp.

Characterization of the vaginal microflora

It is shown that culture remains essential and the most complete picture of the composition of complex microbial communities is obtained by the combination of culture-based with culture-independent approaches.

An association between non-gonococcal urethritis and bacterial vaginosis and the implications for patients and their sexual partners.

An association exists between NGU and BV, and vice versa, and the findings could help to explain the development of urethritis in stable sexual relationships.

The genital econiche: focus on microbiota and bacterial vaginosis

Ecological and evolutionary forces shaping the normal and abnormal microflora of the genital econiche are discussed, in particular those related to bacterial vaginosis, which worldwide is the most

The microbiology of bacterial vaginosis.

  • G. Hill
  • Biology, Medicine
    American journal of obstetrics and gynecology
  • 1993

Anogenital bacteriology in non‐abused preschool children: a descriptive study of the aerobic genital flora and the isolation of anogenital Gardnerella vaginalis

The purpose of the study is to describe the genital aerobic bacterial flora including Gardnerella vaginalis in girls and the occurrence of anal G. vaginalis in both genders. From a group of 3773



Gardnerella vaginalis and anaerobic bacteria in the etiology of bacterial (nonspecific) vaginosis.

Data suggest that as in infections at other mucous membrane sites, bacterial vaginosis is a mixed infection involving a finite number of facultative and anaerobic species and an important role for facultative lactobacilli.

Recovery of anaerobic curved rods and Gardnerella vaginalis from the urethra of men, including male heterosexual consorts of female carriers.

Three hundred and nine men attending a clinic for sexually transmitted diseases were studied regarding urethral colonization with anaerobic curved rods (CR), Gardnerella vaginalis, Bacteroides

Balanoposthitis associated with Gardnerella vaginalis infection in men.

In a second study, concomitant Bacteroides species were isolated in preputial swabs from nine of 12 (75%) men with G vaginalis-associated balanoposthitis and may play a role in its pathogenesis.

Rectal occurrence of Mobiluncus species.

The simultaneous occurrence of Mobiluncus spp in the vagina and rectum was studied in women attending a sexually transmitted diseases (STD) department and BV was cured in nine out of 10 treated with metronidazole and six out of 13 treated with tetracycline.

Comparison of methods for the isolation of genital mycoplasmas from men.

Two hundred nine men were studied to determine the optimal method of obtaining cultures for genital mycoplasma and cultures from the coronal sulcus identified most of the circumcised men who were colonized with M. hominis.


The causal role of H. vaginalis in nonspecific vaginitis, possibly in concert with vaginal anaerobes, and the widespread use of sulfonamide creams is inappropriate is suggested, but its efficacy must be weighed against its possible toxicity.

Clinical and microbiological characterization of patients with nonspecific vaginosis associated with motile, curved anaerobic rods.

The vaginal secretions of normal control subjects and patients with motile, curved anaerobic rods met the criteria of the syndrome of nonspecific vaginosis that has been previously described.

Diagnosis and clinical manifestations of bacterial vaginosis.

Early Postpartum Endometritis: The Role of Bacteria, Genital Mycoplasmas, and Chlamydia trachomatis

Endometrial cultures for facultative and anaerobic bacteria, genital mycoplasmas, and Chlamydia trachomatis were taken with a triple-lumen sampling device to characterize the flora of early postpartum endometritis and the clinical features of women with specific organisms.

Prevalence and significance of Mycoplasma hominis and Ureaplasma urealyticum in the urines of a non-venereal disease population

Overall, ureaplasmas were isolated four times more often than mycoplasmas in mid-stream urines collected from 200 men and 200 women attending hospital with conditions of a non-venereal nature.