Researches on the Intestinal Protozoa of Monkeys and Man

@article{ResearchesOT,
  title={Researches on the Intestinal Protozoa of Monkeys and Man},
  author={},
  journal={Parasitology},
  volume={21},
  pages={446 - 468}
}
  • Published 1 December 1929
  • Biology, Medicine
  • Parasitology
Five tame monkeys (3 Macacus sinicus and 2 M. rhesus) have been treated with emetine bismuthous iodide per os, in order to study the effects of the alkaloid upon their intestinal amoebae (and other protozoa). These monkeys were originally infected with Entamoeba histolytica (large and small strains), Entamoeba coli, Endolimax nana, Enteromonas (= Tricercomonas), and Giardia. Treatment with emetine ultimately eradicated the E. histolytica infections from four out of five animals, but did not… 

References

SHOWING 1-10 OF 17 REFERENCES

Researches on the Intestinal Protozoa of Monkeys and Man. I. General Introduction, and II. Description of the whole Life-History of Entamoeba histolytica in Cultures

The 4-nucleate excysted (metacystic) amoeba has been found to produce a new generation of trophic forms by a complicated series of nuclear and cytoplasmic divisions, which are described in detail for the first time.

EXPERIMENTS ON THE THERAPEUTICS OF AMOEBIC DYSENTERY

It is suggested that the therapeutic efficacy of emetine is a result of its action upon the host rather than upon the parasite in amoebic dysentery, as compared with that of some other alkaloids.

On the Cultivation of Entamoeba histolytica and some other Entozoic Amoebae

Methods by which cultures of entozoic amoebae can be initiated from encysted forms have been discovered and are described, and some indications are given for the isolation of pure strains from mixed cultures.

The Action of Ipecacuanha Alkaloids on Entamoeba histolytica and some other Entozoic Amoebae in Culture

It is now recognized, by all competent observers, that emetine is a specific therapeutic agent for the treatment of amoebic dysentery; but although it is known that a thorough course of emetine, in

Differential Characteristics of the Amoebae of Man in Culture1

There is no remarkable change in structural detail or behavior of the amoebae in their changed environment, and there is found some slight deviation from normal but the main identifying features conform closely to the accepted descriptions.

Further Experiments on the Action of Emetine in Cultures of Entamoeba histolytica

In 1926 two of us published the results of a long series of experiments on the toxic action of the alkaloids of ipecacuanha in cultures of several species of entozoic amoebae, which showed clearly that the full specific action of emetine is only disclosed if the alkAloid is allowed to act for a sufficient time.

INCIDENCE AND TREATMENT OF ENTAMOEBA HISTOLYTICA INFECTION AT WALTON HOSPITAL

Amoebiasis, in: Byam and Archibald, The Practice of Medicine in the Tropics, 2, 1342

  • 1922