Researches on Chemotherapeutic Drugs against Viruses. XXXI. Synthesis and Antiviral Effect of 3-(Alkoxyphenoxy)-1, 2-propanediols on Respiratory Virus.

@article{Ueda1960ResearchesOC,
  title={Researches on Chemotherapeutic Drugs against Viruses. XXXI. Synthesis and Antiviral Effect of 3-(Alkoxyphenoxy)-1, 2-propanediols on Respiratory Virus.},
  author={T. Ueda and S. Toyoshima and K. Takahashi and M. Muraoka and Hiroko Koibuchi and Y. Seto},
  journal={Chemical & Pharmaceutical Bulletin},
  year={1960},
  volume={8},
  pages={921-929}
}
To find chemotherapeutic agents for influenza and adenoviruses, 3-(alkoxyphenoxy)-1, 2-propanediols were synthesized. Among these derivatives, 3-(m-dodecyloxyphenoxy)-1, 2-propanediol possessed a fairly inhibitory effect on the multiplication of the PR-8 strain of influenza virus in chorioallantoic membrane culture. By the primary screening test on the type-1 strain of adenovirus, 3-(p-decyloxyphenoxy)-, 3-(p-dodecyloxyphenoxy)-, 3-(o-hexyloxyphenoxy)-, 3-(o-octyloxyphenoxy)-, 3-(o… Expand
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