Researchers turn off Down’s syndrome genes

@article{Mole2013ResearchersTO,
  title={Researchers turn off Down’s syndrome genes},
  author={Beth Marie Mole},
  journal={Nature},
  year={2013}
}
  • B. Mole
  • Published 17 July 2013
  • Medicine, Biology
  • Nature
Silencing extra chromosome in cell cultures could lead to new treatments for the disorder. 

References

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Translating Dosage Compensation to Trisomy 21
Down’s syndrome is a common disorder with enormous medical and social costs, caused by trisomy for chromosome 21. We tested the concept that gene imbalance across an extra chromosome can be de facto