Research progress on interleukin-33 and its roles in the central nervous system

@article{PingHan2011ResearchPO,
  title={Research progress on interleukin-33 and its roles in the central nervous system},
  author={韩萍 PingHan and Wen-Li Mi 米文丽 and Yan-Qing Wang 王彦青},
  journal={Neuroscience Bulletin},
  year={2011},
  volume={27},
  pages={351-357}
}
Interleukin-33 (IL-33), a newly recognized IL-1 family member, is expressed by various tissues and cells. Since it can combine with chromosomes, IL-33 is regarded as an intracellular transcription repressor. Upon proinflammatory stimulation, it is released as an extracellular cytokine to function as an alarmin to dangerous signals. The IL-33 receptor is a heterodimer complex composed of ST2 and the IL-1 receptor accessory protein, the latter being conserved in other IL-1 family members. The IL… CONTINUE READING
Highly Cited
This paper has 46 citations. REVIEW CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Serum IL-33 Is a Novel Diagnostic and Prognostic Biomarker in Acute Ischemic Stroke

Aging and disease • 2016
View 6 Excerpts
Highly Influenced

IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline.

Proceedings of the National Academy of Sciences of the United States of America • 2016

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Induction of IL-33 expression and activity in central nervous system glia.

Journal of leukocyte biology • 2008
View 20 Excerpts
Highly Influenced

The cytokine interleukin-33 mediates anaphylactic shock.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 5 Excerpts
Highly Influenced

IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice.

Proceedings of the National Academy of Sciences of the United States of America • 2008
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…