Research progress of hydroxychloroquine and autophagy inhibitors on cancer

@article{Shi2016ResearchPO,
  title={Research progress of hydroxychloroquine and autophagy inhibitors on cancer},
  author={Ting-Ting Shi and X C Yu and L M Yan and Hongtao Xiao},
  journal={Cancer Chemotherapy and Pharmacology},
  year={2016},
  volume={79},
  pages={287-294}
}
Hydroxychloroquine (HCQ), the analog of chloroquine, augments the effect of chemotherapies and radiotherapy on various tumors identified in the current clinical trials. Meanwhile, the toxicity of HCQ retinopathy raises concern worldwide. Thus, the potent autophagy inhibitors are urgently needed. A systematic review was related to ‘hydroxychloroquine’ or ‘chloroquine’ with ‘clinical trials,’ ‘retinopathy’ and ‘new autophagy inhibitors.’ This led to many cross-references involving HCQ, and these… CONTINUE READING

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