Research on the nutritional characteristics of medium-chain fatty acids.

@article{Aoyama2007ResearchOT,
  title={Research on the nutritional characteristics of medium-chain fatty acids.},
  author={T. Aoyama and N. Nosaka and M. Kasai},
  journal={The journal of medical investigation : JMI},
  year={2007},
  volume={54 3-4},
  pages={
          385-8
        }
}
Medium-chain fatty acids (MCFA) have attracted attention as part of a healthy diet, because they are absorbed and transported directly into the liver via the portal vein, metabolized rapidly by beta-oxidation, and increase diet-induced thermogenesis. Because medium-chain triacylglycerols (MCT) containing only MCFA has a few weak points as frying oils, we have developed medium- and long-chain triacylglycerols (MLCT). MLCT is produced by lipase-catalyzed enzymatic transesterification. Recently… Expand
Health benefits, enzymatic production, and application of medium- and long-chain triacylglycerol (MLCT) in food industries: a review.
TLDR
This review will discuss on the health benefits of MLCT, its production methods especially via enzymatic processes and its applications in food industries. Expand
A rich medium-chain triacylglycerol diet benefits adiposity but has adverse effects on the markers of hepatic lipogenesis and beta-oxidation.
TLDR
The findings demonstrated that a high amount of MCT (HF-MCT100% group) added to an HF diet reduces the body fat accumulation and insulin resistance, however, the lipid accumulation as well as the lipid metabolism is altered in the liver of animals fed with a very high MCT diet, indicating that higher doses of M CT may be harmful in a long-term. Expand
Medium-chain fatty acid nanoliposomes suppress body fat accumulation in mice
TLDR
MCFA NL could be potential nutritional candidates for obesity to suppress body fat accumulation and overcome the poor palatability of MCFA because the normal diet of mice was maintained. Expand
Short term and dosage influences of palm based medium- and long-chain triacylglycerols on body fat and blood parameters in C57BL/6J mice.
TLDR
From the results, there is a trend that P-MLCT fed mice were found to have the lowest body weight, body weight gain, total fat pad accumulation, total triglyceride levels and efficiency in controlling blood glucose level, compared with C- MLCT and the PKO-PO blend in both low fat and high fat diets. Expand
Medium-chain triglycerides and monounsaturated fatty acids potentiate the beneficial effects of fish oil on selected cardiovascular risk factors in rats.
TLDR
The results suggest that MCTs or MUFAs in the background diet might promote the beneficial effects of FO on CVDs. Expand
Suppression of visceral adipose tissue by palm kernel and soy-canola diacylglycerol in C57BL/6N mice
TLDR
Medium chain type of DG oil, if proven to have similar effects to long chain type DG in this study, can be incorporated into food for health purposes and can replace conventional cooking oil as healthy functional cooking oil. Expand
Fatty acid chain length, postprandial satiety and food intake in lean men
TLDR
It is concluded that there was no evidence that fatty acid chain length has an effect on measures of appetite and food intake when assessed following a single high-fat test meal in lean participants. Expand
Consumption of medium- and long-chain triacylglycerols decreases body fat and blood triglyceride in Chinese hypertriglyceridemic subjects
  • C. Xue, Y. Liu, +11 authors J. Wu
  • Chemistry, Medicine
  • European Journal of Clinical Nutrition
  • 2009
TLDR
Consumption of MLCT may reduce body weight, body fat and blood TG in hypertriglyceridemic subjects under an appropriate dietary regime. Expand
Dietary intake of medium- and long-chain triacylglycerols ameliorates insulin resistance in rats fed a high-fat diet.
TLDR
It is suggested that dietary intake of MLCTs may improve insulin resistance in rats fed a high-fat diet, at least in part through increased adiponectin concentrations caused by a lower mesenteric fat mass. Expand
Preventive Effects of the Dietary Intake of Medium-chain Triacylglycerols on Immobilization-induced Muscle Atrophy in Rats.
TLDR
Results indicate that the dietary intake of MCTs at least partly alleviates immobilization-induced muscle atrophy by inhibiting the ubiquitin-proteasome pathway. Expand
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Effect of dietary medium- and long-chain triacylglycerols (MLCT) on accumulation of body fat in healthy humans.
TLDR
The results suggest that the daily intake of MLCT diet could result in a reduction in body weight and in accumulation of body fat, and, moreover, it could reduce serum total cholesterol. Expand
Medium chain triglycerides and structured lipids
TLDR
In the search for alternative noncarbohydrate fuels, medium chain triglycerides (MCT) are unique and have established themselves in the areas of malabsorption syndrome cases and infant care and as a high energy, rapidly available fuel. Expand
Comparison of diet-induced thermogenesis of foods containing medium- versus long-chain triacylglycerols.
TLDR
It is suggested that, in healthy humans, the intake of 5-10 g of MCT causes larger diet-induced thermogenesis than that of LCT, irrespective of the form of meal containing the MCT. Expand
Dietary medium-chain triacylglycerols suppress accumulation of body fat in a double-blind, controlled trial in healthy men and women.
TLDR
The results suggest that the MCT diet may reduce body weight and fat in individuals (BMI > or = 23 kg/m(2)) more than the LCT diet. Expand
Effect of Medium-Chain Triglycerides on Postprandial Concentrations of Remnant-Like Particles in Healthy Men
A high concentration of remnant-like particles (RLP) has shown to be an arteriosclerosis risk factor that strongly reflects disorders of chylomicron and VLDL metabolism in patients withExpand
Effect of Medium-chain Triglycerides on the Postprandial Triglyceride Concentration in Healthy Men
TLDR
The results suggest that, in subjects with BMI≥23 kg/m2, the intake of MCT is preferable to that of LCT for maintaining postprandial triglyceride at a low concentration. Expand
Medium-chain triglycerides: an update.
A review of the literature on the medical and nutritional use of medium-chain triglycerides (MCTs) since 1970 is presented with additional discussions on the various modifications and applications ofExpand
Thermic effect of medium-chain and long-chain triglycerides in man.
TLDR
The thermic effects of 400 kcal meals of medium-chain triglycerides (MCT) and long-chainlycerides (LCT) were compared in seven healthy men to raise the possibility that long-term substitution of MCT for LCT would produce weight loss if energy intake remained constant. Expand
Relationship between obesity, insulin resistance, and coronary heart disease risk.
TLDR
Obesity and insulin Resistance are both powerful predictors of CHD risk, and insulin resistance at any given degree of obesity accentuates the risk of CHd and type 2 diabetes. Expand
A prospective study of obesity and risk of coronary heart disease in women.
TLDR
Even mild-to-moderate overweight increased the risk of coronary disease in middle-aged women, and the importance of obesity as a determinant of coronary heart disease in women is emphasized. Expand
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