Research on ibuprofen for sepsis and respiratory failure.

  title={Research on ibuprofen for sepsis and respiratory failure.},
  author={Roger C. Bone and Elizabeth R. Jacobs},
  journal={The American journal of medicine},
  volume={77 1A},
According to an experimental study in 26 dogs, ibuprofen reversed the hypotension, increased the cardiac index, prevented the acidosis associated with endotoxic shock, and apparently improved survival. In animals given endotoxin followed by ibuprofen, an initial decrease in systemic blood pressure subsequently recovered to 150.2 +/- 4.1 mm Hg in 120 minutes… CONTINUE READING