Research letterThe gene encoding the biotin-apoprotein ligase of Saccharomyces cerevisiae

@article{Cronan1995ResearchLG,
  title={Research letterThe gene encoding the biotin-apoprotein ligase of Saccharomyces cerevisiae},
  author={John E. Cronan and J. C. Wallace},
  journal={Fems Microbiology Letters},
  year={1995},
  volume={130}
}
  • John E. Cronan, J. C. Wallace
  • Published 1995
  • Biology
  • Fems Microbiology Letters
  • We report the isolation, genomic mapping, and DNA sequence of the BPL1 gene encoding the biotin-apoprotein ligase of Saccharomyces cerevisiae. The gene was isolated by complementation of an Escherichia coli birA (biotin-apoprotein ligase) mutant indicating that the expressed yeast protein modified the essential biotinated protein of the bacterial host. The BPL1 gene encodes a protein of 690 residues (Mr 76.4 kDa) with strong sequence similarites to the E. coli and human biotin-apoprotein… CONTINUE READING