Research and treatment approaches to depression

  title={Research and treatment approaches to depression},
  author={M Wong and Julio Licinio},
  journal={Nature Reviews Neuroscience},
Depression is a major cause of disability worldwide, but we know little about the underlying fundamental biology. Research is hindered by the difficulties of modelling a disorder of higher cognitive functions in animals. Depression can be understood as the interaction of genetic susceptibility and environmental factors; however, current classifications are purely descriptive. The complexity of this field is best approached by rigorous explorations of known candidate systems in conjunction with… CONTINUE READING
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Effects of the high - affinity corticotropin - releasing hormone receptor 1 antagonist R 121919 in major depression : the first 20 patients treated

  • A. W. Zobel
  • J . Psychiatr . Res .
  • 2000

Final data for 1998

  • Murphy, S. L. Deaths
  • National Vital Statistics Reports (CDC) 48, 1–106
  • 2000

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