Research and development for the National Health Service

  title={Research and development for the National Health Service},
  author={Michael Peckham},
  journal={The Lancet},
  • M. Peckham
  • Published 10 August 1991
  • Medicine
  • The Lancet
neuroendocrine probe was too specific for tracking down the 5-HT dependent peripheral marker of OCD. A further contribution on serotonin mechanisms in anorexia nervosa by Kay et al (p. 556) finds elevated concentrations of serotonin metabolites in the CSF of patients. These authors say that this work contributes to the understanding of the psychobiology of the illness. Some cynics may say that the illness is all psycho and no biology, but surely with the advent of a wide range of new seroto… Expand
Assembling Comparison Groups to Assess the Effects of Health care *
  • Lain Chalmers
  • Medicine
  • Journal of the Royal Society of Medicine
  • 1997
Ask what was Bradford Hill's most important specific contribution to knowledge and the answer must surely be his research with Richard Doll on the relation between tobacco and lung cancer. ButExpand
Psychology in health and social care settings: the new opportunities
The first edition of this book was published in 1989. Since then there have been profound and far-reaching changes in the organization and management of health and social care in Great Britain. TheExpand
Patient involvement in health research: a contribution to a systematic review on the effectiveness of treatments for degenerative ataxias.
Patients' perspective is incorporated in the design of a systematic review of scientific literature on the effectiveness of degenerative ataxias treatments to extend the value of systematic reviews to ensure they respond to both clinicians' information needs and patients' expectations. Expand
For debate--Does health care save lives?
  • M. Mckee
  • Medicine
  • Croatian medical journal
  • 1999
There is emerging evidence that reduced access to high quality medical care may contribute to the east-west gap in mortality in Europe and to social inequalities in mortality, and there needs to be a stronger link between public health and health care. Expand
The development of health technology assessment.
While early assessments tended to focus on large, expensive, machine-based technologies, the scope has gradually widened to include smaller technologies, 'softer' technologies (such as counselling), and health care needs, and actual assessments have also taken on broader issues, such as organisational, social, and ethical implications. Expand
Health services research in oncology.
  • P. Selby
  • Medicine
  • British Journal of Cancer
  • 1993
This issue publishes two papers which focus particularly on issues relating to the provision of the Health Service in the United Kingdom and the use of resources and cost implications for the care of patients' advanced breast cancer. Expand
Evidence-based practice: a trainee clinical psychologist perspective
The findings suggest that the SPM may be more accurately termed the reflective-scientist-practitioner, or the critical-reflective-scientists- Practitioner; in acknowledgment of the importance placed on these skills by participants who saw them as central to their role. Expand
A Rationale for Evidence-Based Clinical Supervision
Although modern mental health systems increasingly require evidence-based practice (EBP), clinicians continue to object to restrictions on their professional independence, which they may perceive asExpand
Prenatal corticosteroids for reducing morbidity and mortality after preterm birth, vol. 25.
This Witness Seminar discussed the influence of Liggins' and Howie's 1972 paper announcing results, and subsequent work by Avery and Kotas on induction of pulmonary surfactant in lambs, and other subjects included Crowley's 1981 systematic review of four RCTs. Expand


Effective Care in Pregnancy and Childbirth
  • D. Paintin
  • Medicine
  • British journal of obstetrics and gynaecology
  • 1990
Effective Care in Pregnuncy and Childbir/h, edited by Chalmers, Enkin and Keirse, is probably the most important book in obstetrics to appear this century and its value to the profession will be profound and long lasting. Expand
Assessment, ethics, and the randomized controlled trial.
  • M. Baum
  • Medicine
  • International journal of technology assessment in health care
  • 1989
From the viewpoint of the surgeon, the transaction is equally complex, and his or her decisions may be constrained by resource allocation and time available, however, in the final analysis, assuming a beneficent doctor, the most appropriate decision will be determined by the weight of evidence that can be adduced in favor of any intervention. Expand
Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction.
It is concluded that neither encainide nor flecainide should be used in the treatment of patients with asymptomatic or minimally symptomatic ventricular arrhythmia after myocardial infarction, even though these drugs may be effective initially in suppressing ventricular arrhythmia. Expand
Medical research council European trial of chorion villus sampling
By an indirect calorimetric method, some human ovarian cancer cells resistant to ADR, CDDP, and I-PAM remain sensitive to antitumor PGS. Expand
Use of claims data systems to evaluate health care outcomes. Mortality and reoperation following prostatectomy.
Important differences in death rates between individual hospitals and higher cumulative probability of reoperation following transurethral compared with open prostatectomy are shown. Expand
Clinical trials--are they ethical?
This research aims to improve the quality of life for patients by providing real-time information about the immune system’s response to Epstein-Barr virus. Expand
Priorities in Medical Research
  • D. Mckie
  • Medicine, Political Science
  • The Lancet
  • 1987